Biostimulators

At Lakeside Regenerrative Clinic, biostimulators are injectable treatments designed to stimulate the skin’s natural collagen production and improve skin structure, firmness, and quality over time. Unlike traditional dermal fillers that primarily provide immediate volume, biostimulators work gradually by encouraging the body's own regenerative response.

The choice of biostimulator depends on the patient's skin condition, degree of volume loss, treatment area, medical history, and individual goals.

1. Principle

The principle of biostimulator treatment is to activate the body's natural collagen-producing processes to improve skin structure and restore age-related changes gradually.

Biostimulators may contain materials such as poly-L-lactic acid (PLLA), calcium hydroxylapatite (CaHA), or other clinically established collagen-stimulating substances, depending on the product.

Key principles include:

• Stimulating natural collagen production
• Improving skin firmness and elasticity
• Supporting gradual restoration of facial structure
• Improving skin texture and quality
• Addressing selected areas of age-related volume loss
• Promoting progressive, natural-looking improvement

2. Mechanism

After appropriate injection into the targeted tissue, the biostimulatory material produces a controlled local tissue response.

This response can activate fibroblast activity and collagen synthesis, leading to gradual deposition and remodelling of collagen within the treated area. Depending on the product, some biostimulators may also provide an initial structural or volumising effect.

The resulting improvement develops progressively rather than immediately and varies according to the product, treatment area, injection technique, and individual biological response.

Overall mechanism:

Biostimulator injection → Controlled tissue response → Fibroblast activation → Collagen production → Tissue remodelling → Improved firmness and skin quality

3. Indications

Biostimulator treatments may be considered for patients with:

• Age-related loss of skin firmness
• Reduced skin elasticity
• Fine lines and wrinkles
• Mild to moderate facial volume loss
• Loss of facial definition
• Reduced skin quality and texture
• Early to moderate signs of facial ageing
• Selected areas requiring collagen support

Depending on the specific product, biostimulators may be used in selected areas of the face, neck, décolletage, or other treatment areas.

Treatment selection depends on the patient's anatomy, skin quality, degree of ageing, and desired outcome.

4. Contraindications & Precautions

Biostimulator treatment requires appropriate patient selection and clinical assessment.

Potential contraindications may include:

• Active infection or significant inflammation at the treatment site
• Known hypersensitivity to the product or its components
• Open wounds or significantly compromised skin
• Certain uncontrolled medical conditions
• Previous significant adverse reactions to injectable treatments

Important precautions include:

• Pregnancy and breastfeeding
• Autoimmune or immune-related conditions, depending on the product and clinical circumstances
• Bleeding or clotting disorders
• Use of anticoagulant or antiplatelet medications
• History of abnormal scar formation
• Previous permanent fillers or implants in the proposed treatment area
• Recent facial surgery or other injectable procedures

Patients should provide a complete medical history and disclose all medications, allergies, and previous aesthetic treatments before proceeding.

Biostimulator Treatment at Lakeside Regenerrative Clinic

At Lakeside Regenerrative Clinic, biostimulator treatments are planned according to the patient's facial anatomy, skin quality, degree of collagen loss, and individual treatment goals.

Our team evaluates whether a biostimulator, conventional dermal filler, or another treatment approach is more appropriate for the patient's specific concerns. Patients are counselled about the expected timeline, treatment sessions, limitations, and potential risks before treatment.

Consult our dermatology team to determine whether a biostimulator treatment is suitable for your individual skin and ageing concerns.